Verified & credential-checked
Dr. Elena Marchetti
MD, IFMCP · Functional Medicine Physician
Boulder, Colorado · 17 years in practice
About
Metabolic neurology for APOE4 carriers
Dr. Elena Marchetti completed her internal medicine residency at the University of Colorado and practiced hospital medicine for six years before moving fully into outpatient cognitive prevention. She is certified through the Institute for Functional Medicine and trained in the Bredesen ReCODE protocol.
Her practice is built almost entirely around APOE4 heterozygotes and homozygotes who arrive with a genotype result and no plan. A first visit runs 100 minutes and covers vascular risk, insulin dynamics, sleep architecture, oral microbiome, and toxin exposure history before any intervention is proposed.
She publishes a quarterly review of metabolic markers in cognitive risk and co-supervises a nutrition and coaching team so that testing, food, and behavior stay in one plan rather than three.
Specialties
Approach
A three-phase model, so you know what happens at each stage and what you leave with.
01
Assessment
A 100-minute intake plus a 42-marker panel covering ApoB, fasting insulin, hs-CRP, homocysteine, omega-3 index, thyroid, and sex hormones, with APOE genotyping when it has not already been done.
02
Strategy
Findings are ranked by modifiability and effect size into a written 90-day plan, with one primary lever and no more than three supporting ones so progress is attributable.
03
Execution
Biweekly coaching contact, a 45-day check-in, and a full repeat panel at 90 days. Plans are revised against the numbers, not against how the visit felt.
What clients say
I found out I was APOE4/4 through a research study and spent a year terrified with nobody to call. Dr. Marchetti gave me a plan in one visit and numbers to track. My ApoB dropped 41 points in five months.
She is the first physician who read my whole chart before I walked in. No supplements pushed, no upsell — just a sequence and a follow-up date.
Credentials & Affiliations
Institute for Functional Medicine
American College of Physicians
Alzheimer's Association
American Heart Association